The bus services from Hama will normally deposit you in town, a few hundred metres from the site. It is a short walk up the hill, or you may be offered a ride on a 125cc motorcycle by a who may or may not expect (or demand) money for the service, which should only be a few coins.
Getting around the site is easy, though it is large (several miles in either direction) it is a fairly easy walk. There is no formal disabled access, and much of the site is ruins. Wheelchair access might be possible (the paving in the collonade is still mostly intact), but you'd be trying your luck.
Several Syrian tour companies offer guided tours of the site, which usually include a meal at the restaurant.
The Most Frequently Asked Travel Questions about Apamea
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