New York is a big state, but it's not so big that driving isn't feasible. Even the trip from Buffalo to New York City is only about seven hours—too long for a day trip, certainly, but a weekend trip is doable for the dedicated. An alternative is to take a small regional jet from one of the upstate cities into New York; more expensive, but the trip is only 45-90 minutes in the air. Amtrak also runs trains that connect the five major cities for an in-between solution. If you're headed someplace more out of the way, though, you'll probably need to drive.
The Most Frequently Asked Travel Questions about New York (state)
Where To Stay & Best Hotels in New York (state) - updated May 2024
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New York (state) Travel Guide from Wikitravel. Many thanks to all Wikitravel contributors. Text is available under Creative Commons Attribution-ShareAlike 3.0, images are available under various licenses, see each image for details.